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ECP in solid organ transplantation

By Devon Else

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Apr 7, 2026

Learning objective: After reading this article, learners will be able to describe the procedural workflow and mechanism of action of extracorporeal photopheresis, and its applicability in solid organ transplantation.


Do you know... Which step in extracorporeal photopheresis occurs next after blood is drawn from the patient?

Extracorporeal photopheresis (ECP) is a leukapheresis-based immunomodulatory therapy that has demonstrated efficacy in the treatment of a variety of T-cell-mediated disorders, including solid organ transplant rejection.1 ECP can be performed using either an open or closed system. In a closed system, the ECP device carries out the entire procedure, lowering the risk of infection, contamination, and reinfusion error.1,2

Our educational mini-module describes the procedural workflow and mechanism of action of ECP performed using a closed system.

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This educational resource is independently supported by Therakos. All content was developed by SES in collaboration with an expert steering committee. Funders were allowed no influence on the content of this resource.

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